pentobarbital will minimize the extent or influence of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the extent or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.Avoid coadministration of ganaxolone with reasonable or strong CYP3A4 inducers. If coadm